He was born in Crete, Greece, in 1968, after the primary school, on 25th August 1980 arrived in Jerusalem. He studied at Seminary of the Holly Trinity,
on Mount Zion, Patriarchate of Jerusalem and graduated in 1986. At the same time, he studied English at the American Ulpan in Jerusalem in 1984 and 1985.
On 31st July /13th August 1986, he became a monk and got the name Makarios.
The following year, on 15th/28th February 1987, he was ordained deacon on the Holy Sepulcher by Archbishop of Tabor Daniel. During the academic years 1987-1989 he studied Hebrew at Bet Haam Ulpan, Јеrusalem. On the decision of the Holy Synod of the Patriarchate in Jerusalem he was accepted at the university studies at the Faculty of Divinity of the Serbian Orthodox Church during the academic years 1990/95. After attending a Serbian language course on the first year he graduated on 30th June 1995. His final paper was on Liturgy, the topic being The Church of the Holy Sepulcher in Jerusalem its services throughout centuries.
On 16th / 29th August 1992 he was ordained jeromonk on the Holy Sepulcher by the Archbishop of Tiberias Gregorios and on the day of Transfiguration on Mt. Tabor, 1993, he was promoted Archimandrite from the Patriarch Diodoros. He lectured from 1995- 2002 at Seminary of the Holly Trinity, on Mount Zion and he was the Rector for 6 years at the same Seminary. He appointed director of the Patriarchal Archive from 1995- 2001. During the academic year 2000-2001 he studied Russian language at Bet Haam Ulpan, Jerusalem. On the decision of the Holy Synod September 2002 appointed in Fuhais Jordan. During the academic year 2002-2003 he attended an Arabic language course at the Faculty of Philology, University of Jordan in Amman.On the decision of the Holy Synod October 2004 promoted Patriarchal Representative of Qatar.
He has written numerous articles and participated in various conferences.